Study Overview
Very little is known about using antidepressants in patients living with bipolar depression. Antidepressants can be very effective in people with depression and can also be prescribed by a GP.
In this study, we will use a combination of an antidepressant (sertraline) and an antipsychotic (aripiprazole) and compare this combination with an antipsychotic medication called quetiapine. Quetiapine is a common treatment for people experiencing depression in bipolar disorder.
All three medications are already used in the NHS, but we want to find out if using a sertraline/aripiprazole combination will be beneficial in reducing depressive symptoms in people with bipolar disorder.
To do this, we are looking for 270 patients with bipolar who are currently experiencing a depressive phase from across the England to take part in the study.
Click the button below to find out more about eligibility requirements and recruitment processes.
